• Flexible output data, result turnaround time, and cost per sample to meet research needs • Flexible flow cell and read length configuration to accommodate multiple applications • Increased efficiency through simplified workflow and reduced manual operation time • "Load-and-run" reagent cartridge design reduces reagent consumption by up to 80% compared to HiSeq systems • Ready-to-use reagents, just thaw and gently invert, no complex preparation required, eliminating user intervention, minimizing errors, and significantly shortening setup time • Reagent consumables encoded with RFID (Radio-Frequency Identification) technology enable automatic reagent tracking and ensure compatibility between all reagents and flow cells • Automated flow cell loading and cluster generation directly on the instrument reduce manual operation time • Extended reagent shelf life optimizes planning for future projects • Optional 35-cycle kit expands workflow processes, including COVIDSeq™ applications and quantification, while reducing cost per read • Advanced reagent chemistry technology streamlines processes, increases the number of unique molecular identifiers (UMIs) to support more complex tasks, and is compatible with the entire Illumina library preparation solution

Flow Cell TypeSPS1S2S4
Number of lanes per flow cell2224
Output capacity per flow cell
1 × 35 bpN/AN/AN/A280-350 Gb
2 × 50 bp65-80 Gb134-167 Gb333-417 GbN/A
2 × 100 bp134-167 Gb266-333 Gb667-833 Gb1600- 2000 Gb
2 × 150 bp200-250 Gb400-500 Gb1000- 1250 Gb2400- 3000 Gb
2 × 250 bp325-400 GbN/AN/AN/A
Single Read CPF0.65-0.8B1.3-1.6B3.3-4.1B8-10B
Paired End CPF1.3-1.6B2.6-3.2B6.6-8.2B16-20B
Quality Metrics
1 × 35 bpQ30 ≥ 90%
2 × 50 bpQ30 ≥ 90%
2 × 100 bpQ30 ≥ 85%
2 × 150 bpQ30 ≥ 85%
2 × 250 bpQ30 ≥ 75%
Average Run Time
1 × 35 bpN/AN/AN/A~ 14 hr
2 × 50 bp~ 13 hr~ 13 hr~ 16 hrN/A
2 × 100 bp~ 19 hr~ 19 hr~ 25 hr~ 36 hr
2 × 150 bp~ 25 hr~ 25 hr~ 36 hr~ 44 hr
2 × 250 bp~ 38 hrN/AN/AN/A